Long-term side-effects in testicular cancer could be reduced by chemotherapy before radiotherapy

Main Category: Cancer / Oncology
Also Included In: Radiology / Nuclear Medicine
Article Date: 20 Aug 2013 - 0:00 PDT Current ratings for:
Long-term side-effects in testicular cancer could be reduced by chemotherapy before radiotherapy

Giving men with testicular cancer a single dose of chemotherapy alongside radiotherapy could improve the effectiveness of treatment and reduce the risk of long-term side-effects, a new study reports. As many as 96% of men with testicular cancer now survive at least ten years from diagnosis (1), but more advanced forms need to be treated with combination chemotherapy - which can have serious long-term complications. Researchers at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust have therefore been searching for new treatments that would reduce the risk of relapse after initial treatment and so spare as many men as possible from needing combination chemotherapy.

The new pilot study, published in the August issue of prestigious journal the Annals of Oncology, tested a new treatment in a pilot study of men with stage IIA and IIB testicular seminoma - where the cancer has spread to the lymph nodes in the abdomen.

The researchers showed that giving chemotherapy drug carboplatin before radiotherapy could reduce relapse rates compared with radiotherapy alone - cutting the numbers of men who would need follow-up treatment. It also allowed radiation doses to be reduced. The study was funded by The Institute of Cancer Research (ICR), the Bob Champion Cancer Trust and Cancer Research UK, as well as through the NIHR Biomedical Research Centre at The Royal Marsden and the ICR.

Researchers gave 51 men with stage IIA and IIB testicular seminoma a single cycle of carboplatin - a low toxicity form of chemotherapy - followed three to four weeks later by radiotherapy. Most of the men were aged below 50, over a range of 18-73 years.

Adding carboplatin to patients' treatment plans allowed doctors to give a lower dose of radiation over a smaller area of the body for most of the men in the study. Some 39 of the men in the study had their prescription of radiation reduced from the standard 35 Grays (Gy) of radiation to 30 Gy, delivered to a smaller area of the abdomen.

After an average of 4.5 years of follow-up, there were no relapses of the cancer compared with a relapse risk of 5-11% after radiotherapy alone. The side-effects from treatment were mild and only lasted a short time.

Dr Robert Huddart, Team Leader in the Division of Radiation and Imaging at the Institute of Cancer Research, London, and Consultant at The Royal Marsden, who led the study, said:

"The results of this study show great promise. Men who have this stage of testicular seminoma are normally treated with just radiotherapy, or in some countries with intensive combination chemotherapy, where several anticancer drugs are given at once. Relapse occurs in 5-11% of men after radiotherapy alone, and these recurrences have to be treated with combination chemotherapy, which is associated with a risk of serious long-term complications such as cardiovascular disease or second cancers.

"The aim of the study was to develop an effective non-toxic treatment with low risk of long-term treatment complications, and our findings suggest that a single cycle of carboplatin before radiotherapy may reduce the chances of cancer reappearing compared with radiotherapy alone. This will reduce the risk that these patients would need combination chemotherapy. Not only that, but by adding carboplatin to the therapy, the radiation dose and volume can be lowered."

As this was a small, single-centre study, the researchers are recommending the approach is evaluated more widely.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our cancer / oncology section for the latest news on this subject.

(1) Cancer Research UK Testicular cancer survival statistics (2009). Accessed online 15 August 2013.

Neoadjuvant carboplatin before radiotherapy in stage IIA and IIB seminoma

Ann Oncol (2013) 24 (8): 2104-2107. doi: 10.1093/annonc/mdt148

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Should You Try Botox? What We Wish We'd Known Before We Did

From wrinkles to migraines to happy faces, women share why they jumped on the Botox bandwagon

By Jeannette Moninger - June 26, 2013

It’s not just Real Housewives and Hollywood stars who want to stay youthful. In 2012, a record-setting 6.1 million Americans (94 percent of them women) received Botox injections. While some turn to the procedure to fight migraines or excessive sweating, the majority simply want to look younger. Here, women reveal the good, the bad and the ugly truth they learned from getting Botox.

Beware the Dog Face
“I loved how Botox softened my crow’s feet, so I tried it for frown lines between my brows. The effects were great — until I cried (and I cry often out of joy, sadness, hormonal reasons, you name it!). My inner eyebrows stayed the same, but the lower sections moved down giving me a basset hound appearance. I am an emotionally expressive person, so I will not be repeating that procedure.” —Stacey, age 45

It Can Cure Your 'Anger' Problem
“The deep crease between my eyebrows always made me look angry even when I was in great spirits. Without that line, I look so much more relaxed and youthful—happy even!” —Tina, age 48

Your Face Might Spasm
“When my Botox started to wear off, it felt like my forehead was having muscle spasms and contracting my eyebrows up toward my scalp. Thankfully, these spasms weren’t noticeable to others, but the sensation (which lasted for days) was very strange and really annoying.” —Sarah, age 44

You’ll Start Seeing Wrinkles Everywhere
“Since starting Botox, I’m very aware of how wrinkly other people’s foreheads are. But I would never tell my friends that.” —Ashlie, age 21

This Is Not the Time to Bargain Hunt
“I once experienced significant swelling after going to an inexperienced clinician. Ask your friends who they recommend and make sure the technician is well trained.” —Marisa, age 51

You Need to Be Realistic
“Botox isn’t a facelift-in-a-bottle. As a registered nurse who has both given and received injections, I find that most women’s expectations are too high. Botox is great at diminishing mild to moderate facial lines and wrinkles, but it won’t help saggy skin or deeply-etched lines. A good clinician should outline the changes you can realistically expect.” —Beth, age 52

It Really Can Prevent Migraines
“Getting Botox for migraines is like being stung repeatedly in the head. Still the pain is nothing compared to an actual migraine. My migraines have gone from about 15 a month to half that. It’s a win-win: Less pain and fewer wrinkles!” —Kari, age 44

It'll Stop Drippy Armpits
“My underarms used to drip before I started getting Botox for excessive sweating. The twice-yearly injections — about 20 per armpit — are not fun, but the payoff is sweet smelling.” —Robin, age 51

You Could Get Hooked
“At first I didn’t think I needed Botox. Now I’m scared to stop because I love what it has done for me. I feel younger, prettier and more confident” —Melissa, age 35

It's Not Just for Women With Wrinkles
“When deep creases started lining my forehead at age 27, I knew they’d only become deeper and more noticeable with age. I use Botox not necessarily to look younger, but to ensure that I won’t look older.” —Michelle, age 30

Connect with Us Follow Our Pins

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View the original article here

There’s a Black Market for Botox & Other Things to Know Before Getting Injected

Botox might take years off your appearance, but before requesting your own injectable Fountain of Youth, make sure you know exactly what you're doing

By Kristin Booker - July 5, 2013

Botox Might Not Do What You Want It to
Many people confuse what Botox actually does with other age-fighting beauty injectables. “[Botox's] only benefit is to render a muscle weaker for 3-4 months. It doesn't fill lines, it just makes it harder to make the muscle contraction that creates the lines,” explains board-certified dermatologist Dr. Misbah Khan, owner of M. Khan Dermatology in New York City. So will it work on those wrinkles around the mouth? “No. If you have smile lines [the parentheses around the mouth], you'll need a filler [like Restylane] to erase them.”

There's a Black Market
Many coupon services run deals for cheap series of Botox, and they’re probably all too good to be true. Before you buy into anything, know who and what you’re dealing with. “Do not look for the better deal. Make sure you know what’s going in your face. If it's too cheap, it may be acquired on the black market, or the Botox they’re using might be expired or about to expire," warns Dr. Khan.

You Could Have an Allergic Reaction
You may know that Botox is derived from the same bacteria as the toxin botulism, and while you absolutely cannot catch botulism from the use of Botox, there is a small chance that you could have an allergic reaction to preservatives and ingredients used. "Some reactions that have been reported include itching, rash, welts, asthma symptoms or feeling faint,” says Dr. Dennis Gross, founder of 900 5th Dermatology and creator of Dr. Dennis Gross Skincare. If you do have a reaction, call your doctor right away.

An Unskilled Injector Might Leave You Lopsided
“If the Botox is injected wrong in any part of your face, you may have a lopsided appearance,” says Dr. Gross. “Just remember that there is an artistry involved in the technique, so be sure your physician is highly experienced and skilled at administering it.”

Overdoing It Could Lead to Drooping—or Worse
“Drooping of the eyebrows can happen even in the best of hands; it can occur if too much is injected in one place,” says Dr. Khan. And if you’re already using Botox, over-application could make it worse. “Overuse of Botox can cause the muscles to become so weak that they can't support the flesh.” The results can look unnatural, and even worse, be painful. “If too much Botox is applied during a neck rejuvenation, it can cause the side of the face to droop, or in some cases the muscles that hold the neck up weaken to the point where you can't swallow or hold your head up."

Speaking Up Can Divert Disaster
You might think that you really, really want Botox no matter the small risks, but the pursuit of beauty is never worth harming your health. As with any other procedure, you should always disclose your full medical history before sitting in the chair. “Make sure to tell your doctor about all of your muscle or nerve conditions, as you may have an increased risk of serious side-effects, including difficulty swallowing and/or breathing,” cautions Dr. Gross. “Also, inform your doctor of any surgery plans, weakness of forehead muscles, recent injections, or medicines you are currently taking.” Dr. Gervaise Gerstner, L’Oréal Paris Consulting Dermatologist adds one more caution to that list: “Be sure to disclose any autoimmune neuromotor disease like myasenthia gravis.”

Results Are Not Instant
“It takes about three to seven days to show the full effect, and results will last about four months,” says Dr. Gross. And those results vary, depending on the depth of your wrinkles. “If you start Botox treatments just as fine lines are beginning to appear and continue them as you age, you can prevent select expression lines from forming at all,” advises Dr. Gross. Patients who already have pronounced lines may see benefits in a bit more time, “It takes a few days to see results, and a full two weeks to see the full effects of a Botox treatment,” explains Dr. Khan.

Botox is Not Painless
Although getting Botox is not particularly painful for most patients, since there are needles involved, you can’t expect to feel absolutely nothing when getting injected. “During the procedure, you can expect a slight pinch from the needle. There are numbing creams available in topical and aesthetic forms,” says Dr. Gross. Dr. Khan is also known to use ice to numb the area for people who have a low tolerance or phobia of needles.

Aspirin and Fish Oil Don't Mix With Botox
“We tell our patients to stop using aspirin products up to a week before a treatment because they are blood thinners,” cautions Dr. Gross. "Discontinuing the use of aspirin the week before will help to keep bruising down. Also, we tell our patients to stop using fish oils a week beforehand because they also promote bruising for the same blood thinning reason.” Of course, always discuss changing the dosage of medicine with your primary physician beforehand.

Hair-Drying Is Off Limits Right After the Procedure
“There’s no lowering of the head for two hours post-procedure,” says Dr. Gerstner. “No yoga, no bending over, no blow drying your hair, no tight hats, no napping. In other words, heads up!”

It Might Cure More Than Wrinkles
If you have excessive underarm or palm sweating or suffer from serious migraines, talk to your doctor about using Botox to cure these ills. It's been proven to diminish or stop excessive sweating, called hyperhidrosis, and to reduce the severity of migraines too—but don’t try tacking either treatment onto your cosmetic visit. You’ll need to book separate appointments. One quick tip: always take a quick peek at the box. “Botox meant for cosmetic purposes will say ‘Botox Cosmetic’ on the packaging,” says Dr. Khan. “Botox for medical purposes will say that on the package.”

A Happier Look Might Actually Improve Your Mood
If you’re prone to frowning, “eventually those muscles strengthen in that formation, which means it takes much effort to smile and look happy. When Botox relaxes those muscles, you look happier, which can really improve your mood and confidence,” says Dr. Gross.

Kristin Booker is a contributing writer on iVillage. Follow her on Twitter andGoogle+.

Connect with Us Follow Our Pins

Yummy recipes, DIY projects, home decor, fashion and more curated by iVillage staffers.

The very dirty truth about fashion internships... DUN DUN @srslytheshow http://t.co/wfewf

On Instagram

Behind-the-scenes pics from iVillage.

View the original article here

Should You Try Botox? What We Wish We'd Known Before We Did

From wrinkles to migraines to happy faces, women share why they jumped on the Botox bandwagon

By Jeannette Moninger - June 26, 2013

It’s not just Real Housewives and Hollywood stars who want to stay youthful. In 2012, a record-setting 6.1 million Americans (94 percent of them women) received Botox injections. While some turn to the procedure to fight migraines or excessive sweating, the majority simply want to look younger. Here, women reveal the good, the bad and the ugly truth they learned from getting Botox.

Beware the Dog Face
“I loved how Botox softened my crow’s feet, so I tried it for frown lines between my brows. The effects were great — until I cried (and I cry often out of joy, sadness, hormonal reasons, you name it!). My inner eyebrows stayed the same, but the lower sections moved down giving me a basset hound appearance. I am an emotionally expressive person, so I will not be repeating that procedure.” —Stacey, age 45

It Can Cure Your 'Anger' Problem
“The deep crease between my eyebrows always made me look angry even when I was in great spirits. Without that line, I look so much more relaxed and youthful—happy even!” —Tina, age 48

Your Face Might Spasm
“When my Botox started to wear off, it felt like my forehead was having muscle spasms and contracting my eyebrows up toward my scalp. Thankfully, these spasms weren’t noticeable to others, but the sensation (which lasted for days) was very strange and really annoying.” —Sarah, age 44

You’ll Start Seeing Wrinkles Everywhere
“Since starting Botox, I’m very aware of how wrinkly other people’s foreheads are. But I would never tell my friends that.” —Ashlie, age 21

This Is Not the Time to Bargain Hunt
“I once experienced significant swelling after going to an inexperienced clinician. Ask your friends who they recommend and make sure the technician is well trained.” —Marisa, age 51

You Need to Be Realistic
“Botox isn’t a facelift-in-a-bottle. As a registered nurse who has both given and received injections, I find that most women’s expectations are too high. Botox is great at diminishing mild to moderate facial lines and wrinkles, but it won’t help saggy skin or deeply-etched lines. A good clinician should outline the changes you can realistically expect.” —Beth, age 52

It Really Can Prevent Migraines
“Getting Botox for migraines is like being stung repeatedly in the head. Still the pain is nothing compared to an actual migraine. My migraines have gone from about 15 a month to half that. It’s a win-win: Less pain and fewer wrinkles!” —Kari, age 44

It'll Stop Drippy Armpits
“My underarms used to drip before I started getting Botox for excessive sweating. The twice-yearly injections — about 20 per armpit — are not fun, but the payoff is sweet smelling.” —Robin, age 51

You Could Get Hooked
“At first I didn’t think I needed Botox. Now I’m scared to stop because I love what it has done for me. I feel younger, prettier and more confident” —Melissa, age 35

It's Not Just for Women With Wrinkles
“When deep creases started lining my forehead at age 27, I knew they’d only become deeper and more noticeable with age. I use Botox not necessarily to look younger, but to ensure that I won’t look older.” —Michelle, age 30

Connect with Us Follow Our Pins

Yummy recipes, DIY projects, home decor, fashion and more curated by iVillage staffers.

The very dirty truth about fashion internships... DUN DUN @srslytheshow http://t.co/wfewf

On Instagram

Behind-the-scenes pics from iVillage.

View the original article here

There’s a Black Market for Botox & Other Things to Know Before Getting Injected

Botox might take years off your appearance, but before requesting your own injectable Fountain of Youth, make sure you know exactly what you're doing

By Kristin Booker - July 5, 2013

Botox Might Not Do What You Want It to
Many people confuse what Botox actually does with other age-fighting beauty injectables. “[Botox's] only benefit is to render a muscle weaker for 3-4 months. It doesn't fill lines, it just makes it harder to make the muscle contraction that creates the lines,” explains board-certified dermatologist Dr. Misbah Khan, owner of M. Khan Dermatology in New York City. So will it work on those wrinkles around the mouth? “No. If you have smile lines [the parentheses around the mouth], you'll need a filler [like Restylane] to erase them.”

There's a Black Market
Many coupon services run deals for cheap series of Botox, and they’re probably all too good to be true. Before you buy into anything, know who and what you’re dealing with. “Do not look for the better deal. Make sure you know what’s going in your face. If it's too cheap, it may be acquired on the black market, or the Botox they’re using might be expired or about to expire," warns Dr. Khan.

You Could Have an Allergic Reaction
You may know that Botox is derived from the same bacteria as the toxin botulism, and while you absolutely cannot catch botulism from the use of Botox, there is a small chance that you could have an allergic reaction to preservatives and ingredients used. "Some reactions that have been reported include itching, rash, welts, asthma symptoms or feeling faint,” says Dr. Dennis Gross, founder of 900 5th Dermatology and creator of Dr. Dennis Gross Skincare. If you do have a reaction, call your doctor right away.

An Unskilled Injector Might Leave You Lopsided
“If the Botox is injected wrong in any part of your face, you may have a lopsided appearance,” says Dr. Gross. “Just remember that there is an artistry involved in the technique, so be sure your physician is highly experienced and skilled at administering it.”

Overdoing It Could Lead to Drooping—or Worse
“Drooping of the eyebrows can happen even in the best of hands; it can occur if too much is injected in one place,” says Dr. Khan. And if you’re already using Botox, over-application could make it worse. “Overuse of Botox can cause the muscles to become so weak that they can't support the flesh.” The results can look unnatural, and even worse, be painful. “If too much Botox is applied during a neck rejuvenation, it can cause the side of the face to droop, or in some cases the muscles that hold the neck up weaken to the point where you can't swallow or hold your head up."

Speaking Up Can Divert Disaster
You might think that you really, really want Botox no matter the small risks, but the pursuit of beauty is never worth harming your health. As with any other procedure, you should always disclose your full medical history before sitting in the chair. “Make sure to tell your doctor about all of your muscle or nerve conditions, as you may have an increased risk of serious side-effects, including difficulty swallowing and/or breathing,” cautions Dr. Gross. “Also, inform your doctor of any surgery plans, weakness of forehead muscles, recent injections, or medicines you are currently taking.” Dr. Gervaise Gerstner, L’Oréal Paris Consulting Dermatologist adds one more caution to that list: “Be sure to disclose any autoimmune neuromotor disease like myasenthia gravis.”

Results Are Not Instant
“It takes about three to seven days to show the full effect, and results will last about four months,” says Dr. Gross. And those results vary, depending on the depth of your wrinkles. “If you start Botox treatments just as fine lines are beginning to appear and continue them as you age, you can prevent select expression lines from forming at all,” advises Dr. Gross. Patients who already have pronounced lines may see benefits in a bit more time, “It takes a few days to see results, and a full two weeks to see the full effects of a Botox treatment,” explains Dr. Khan.

Botox is Not Painless
Although getting Botox is not particularly painful for most patients, since there are needles involved, you can’t expect to feel absolutely nothing when getting injected. “During the procedure, you can expect a slight pinch from the needle. There are numbing creams available in topical and aesthetic forms,” says Dr. Gross. Dr. Khan is also known to use ice to numb the area for people who have a low tolerance or phobia of needles.

Aspirin and Fish Oil Don't Mix With Botox
“We tell our patients to stop using aspirin products up to a week before a treatment because they are blood thinners,” cautions Dr. Gross. "Discontinuing the use of aspirin the week before will help to keep bruising down. Also, we tell our patients to stop using fish oils a week beforehand because they also promote bruising for the same blood thinning reason.” Of course, always discuss changing the dosage of medicine with your primary physician beforehand.

Hair-Drying Is Off Limits Right After the Procedure
“There’s no lowering of the head for two hours post-procedure,” says Dr. Gerstner. “No yoga, no bending over, no blow drying your hair, no tight hats, no napping. In other words, heads up!”

It Might Cure More Than Wrinkles
If you have excessive underarm or palm sweating or suffer from serious migraines, talk to your doctor about using Botox to cure these ills. It's been proven to diminish or stop excessive sweating, called hyperhidrosis, and to reduce the severity of migraines too—but don’t try tacking either treatment onto your cosmetic visit. You’ll need to book separate appointments. One quick tip: always take a quick peek at the box. “Botox meant for cosmetic purposes will say ‘Botox Cosmetic’ on the packaging,” says Dr. Khan. “Botox for medical purposes will say that on the package.”

A Happier Look Might Actually Improve Your Mood
If you’re prone to frowning, “eventually those muscles strengthen in that formation, which means it takes much effort to smile and look happy. When Botox relaxes those muscles, you look happier, which can really improve your mood and confidence,” says Dr. Gross.

Kristin Booker is a contributing writer on iVillage. Follow her on Twitter andGoogle+.

Connect with Us Follow Our Pins

Yummy recipes, DIY projects, home decor, fashion and more curated by iVillage staffers.

The very dirty truth about fashion internships... DUN DUN @srslytheshow http://t.co/wfewf

On Instagram

Behind-the-scenes pics from iVillage.

View the original article here

There’s a Black Market for Botox & Other Things to Know Before Getting Injected

Botox might take years off your appearance, but before requesting your own injectable Fountain of Youth, make sure you know exactly what you're doing

By Kristin Booker - July 5, 2013

Botox Might Not Do What You Want It to
Many people confuse what Botox actually does with other age-fighting beauty injectables. “[Botox's] only benefit is to render a muscle weaker for 3-4 months. It doesn't fill lines, it just makes it harder to make the muscle contraction that creates the lines,” explains board-certified dermatologist Dr. Misbah Khan, owner of M. Khan Dermatology in New York City. So will it work on those wrinkles around the mouth? “No. If you have smile lines [the parentheses around the mouth], you'll need a filler [like Restylane] to erase them.”

There's a Black Market
Many coupon services run deals for cheap series of Botox, and they’re probably all too good to be true. Before you buy into anything, know who and what you’re dealing with. “Do not look for the better deal. Make sure you know what’s going in your face. If it's too cheap, it may be acquired on the black market, or the Botox they’re using might be expired or about to expire," warns Dr. Khan.

You Could Have an Allergic Reaction
You may know that Botox is derived from the same bacteria as the toxin botulism, and while you absolutely cannot catch botulism from the use of Botox, there is a small chance that you could have an allergic reaction to preservatives and ingredients used. "Some reactions that have been reported include itching, rash, welts, asthma symptoms or feeling faint,” says Dr. Dennis Gross, founder of 900 5th Dermatology and creator of Dr. Dennis Gross Skincare. If you do have a reaction, call your doctor right away.

An Unskilled Injector Might Leave You Lopsided
“If the Botox is injected wrong in any part of your face, you may have a lopsided appearance,” says Dr. Gross. “Just remember that there is an artistry involved in the technique, so be sure your physician is highly experienced and skilled at administering it.”

Overdoing It Could Lead to Drooping—or Worse
“Drooping of the eyebrows can happen even in the best of hands; it can occur if too much is injected in one place,” says Dr. Khan. And if you’re already using Botox, over-application could make it worse. “Overuse of Botox can cause the muscles to become so weak that they can't support the flesh.” The results can look unnatural, and even worse, be painful. “If too much Botox is applied during a neck rejuvenation, it can cause the side of the face to droop, or in some cases the muscles that hold the neck up weaken to the point where you can't swallow or hold your head up."

Speaking Up Can Divert Disaster
You might think that you really, really want Botox no matter the small risks, but the pursuit of beauty is never worth harming your health. As with any other procedure, you should always disclose your full medical history before sitting in the chair. “Make sure to tell your doctor about all of your muscle or nerve conditions, as you may have an increased risk of serious side-effects, including difficulty swallowing and/or breathing,” cautions Dr. Gross. “Also, inform your doctor of any surgery plans, weakness of forehead muscles, recent injections, or medicines you are currently taking.” Dr. Gervaise Gerstner, L’Oréal Paris Consulting Dermatologist adds one more caution to that list: “Be sure to disclose any autoimmune neuromotor disease like myasenthia gravis.”

Results Are Not Instant
“It takes about three to seven days to show the full effect, and results will last about four months,” says Dr. Gross. And those results vary, depending on the depth of your wrinkles. “If you start Botox treatments just as fine lines are beginning to appear and continue them as you age, you can prevent select expression lines from forming at all,” advises Dr. Gross. Patients who already have pronounced lines may see benefits in a bit more time, “It takes a few days to see results, and a full two weeks to see the full effects of a Botox treatment,” explains Dr. Khan.

Botox is Not Painless
Although getting Botox is not particularly painful for most patients, since there are needles involved, you can’t expect to feel absolutely nothing when getting injected. “During the procedure, you can expect a slight pinch from the needle. There are numbing creams available in topical and aesthetic forms,” says Dr. Gross. Dr. Khan is also known to use ice to numb the area for people who have a low tolerance or phobia of needles.

Aspirin and Fish Oil Don't Mix With Botox
“We tell our patients to stop using aspirin products up to a week before a treatment because they are blood thinners,” cautions Dr. Gross. "Discontinuing the use of aspirin the week before will help to keep bruising down. Also, we tell our patients to stop using fish oils a week beforehand because they also promote bruising for the same blood thinning reason.” Of course, always discuss changing the dosage of medicine with your primary physician beforehand.

Hair-Drying Is Off Limits Right After the Procedure
“There’s no lowering of the head for two hours post-procedure,” says Dr. Gerstner. “No yoga, no bending over, no blow drying your hair, no tight hats, no napping. In other words, heads up!”

It Might Cure More Than Wrinkles
If you have excessive underarm or palm sweating or suffer from serious migraines, talk to your doctor about using Botox to cure these ills. It's been proven to diminish or stop excessive sweating, called hyperhidrosis, and to reduce the severity of migraines too—but don’t try tacking either treatment onto your cosmetic visit. You’ll need to book separate appointments. One quick tip: always take a quick peek at the box. “Botox meant for cosmetic purposes will say ‘Botox Cosmetic’ on the packaging,” says Dr. Khan. “Botox for medical purposes will say that on the package.”

A Happier Look Might Actually Improve Your Mood
If you’re prone to frowning, “eventually those muscles strengthen in that formation, which means it takes much effort to smile and look happy. When Botox relaxes those muscles, you look happier, which can really improve your mood and confidence,” says Dr. Gross.

Kristin Booker is a contributing writer on iVillage. Follow her on Twitter andGoogle+.

Connect with Us Follow Our Pins

Yummy recipes, DIY projects, home decor, fashion and more curated by iVillage staffers.

The very dirty truth about fashion internships... DUN DUN @srslytheshow http://t.co/wfewf

On Instagram

Behind-the-scenes pics from iVillage.

View the original article here

There’s a Black Market for Botox & Other Things to Know Before Getting Injected

Botox might take years off your appearance, but before requesting your own injectable Fountain of Youth, make sure you know exactly what you're doing

By Kristin Booker - July 5, 2013

Botox Might Not Do What You Want It to
Many people confuse what Botox actually does with other age-fighting beauty injectables. “[Botox's] only benefit is to render a muscle weaker for 3-4 months. It doesn't fill lines, it just makes it harder to make the muscle contraction that creates the lines,” explains board-certified dermatologist Dr. Misbah Khan, owner of M. Khan Dermatology in New York City. So will it work on those wrinkles around the mouth? “No. If you have smile lines [the parentheses around the mouth], you'll need a filler [like Restylane] to erase them.”

There's a Black Market
Many coupon services run deals for cheap series of Botox, and they’re probably all too good to be true. Before you buy into anything, know who and what you’re dealing with. “Do not look for the better deal. Make sure you know what’s going in your face. If it's too cheap, it may be acquired on the black market, or the Botox they’re using might be expired or about to expire," warns Dr. Khan.

You Could Have an Allergic Reaction
You may know that Botox is derived from the same bacteria as the toxin botulism, and while you absolutely cannot catch botulism from the use of Botox, there is a small chance that you could have an allergic reaction to preservatives and ingredients used. "Some reactions that have been reported include itching, rash, welts, asthma symptoms or feeling faint,” says Dr. Dennis Gross, founder of 900 5th Dermatology and creator of Dr. Dennis Gross Skincare. If you do have a reaction, call your doctor right away.

An Unskilled Injector Might Leave You Lopsided
“If the Botox is injected wrong in any part of your face, you may have a lopsided appearance,” says Dr. Gross. “Just remember that there is an artistry involved in the technique, so be sure your physician is highly experienced and skilled at administering it.”

Overdoing It Could Lead to Drooping—or Worse
“Drooping of the eyebrows can happen even in the best of hands; it can occur if too much is injected in one place,” says Dr. Khan. And if you’re already using Botox, over-application could make it worse. “Overuse of Botox can cause the muscles to become so weak that they can't support the flesh.” The results can look unnatural, and even worse, be painful. “If too much Botox is applied during a neck rejuvenation, it can cause the side of the face to droop, or in some cases the muscles that hold the neck up weaken to the point where you can't swallow or hold your head up."

Speaking Up Can Divert Disaster
You might think that you really, really want Botox no matter the small risks, but the pursuit of beauty is never worth harming your health. As with any other procedure, you should always disclose your full medical history before sitting in the chair. “Make sure to tell your doctor about all of your muscle or nerve conditions, as you may have an increased risk of serious side-effects, including difficulty swallowing and/or breathing,” cautions Dr. Gross. “Also, inform your doctor of any surgery plans, weakness of forehead muscles, recent injections, or medicines you are currently taking.” Dr. Gervaise Gerstner, L’Oréal Paris Consulting Dermatologist adds one more caution to that list: “Be sure to disclose any autoimmune neuromotor disease like myasenthia gravis.”

Results Are Not Instant
“It takes about three to seven days to show the full effect, and results will last about four months,” says Dr. Gross. And those results vary, depending on the depth of your wrinkles. “If you start Botox treatments just as fine lines are beginning to appear and continue them as you age, you can prevent select expression lines from forming at all,” advises Dr. Gross. Patients who already have pronounced lines may see benefits in a bit more time, “It takes a few days to see results, and a full two weeks to see the full effects of a Botox treatment,” explains Dr. Khan.

Botox is Not Painless
Although getting Botox is not particularly painful for most patients, since there are needles involved, you can’t expect to feel absolutely nothing when getting injected. “During the procedure, you can expect a slight pinch from the needle. There are numbing creams available in topical and aesthetic forms,” says Dr. Gross. Dr. Khan is also known to use ice to numb the area for people who have a low tolerance or phobia of needles.

Aspirin and Fish Oil Don't Mix With Botox
“We tell our patients to stop using aspirin products up to a week before a treatment because they are blood thinners,” cautions Dr. Gross. "Discontinuing the use of aspirin the week before will help to keep bruising down. Also, we tell our patients to stop using fish oils a week beforehand because they also promote bruising for the same blood thinning reason.” Of course, always discuss changing the dosage of medicine with your primary physician beforehand.

Hair-Drying Is Off Limits Right After the Procedure
“There’s no lowering of the head for two hours post-procedure,” says Dr. Gerstner. “No yoga, no bending over, no blow drying your hair, no tight hats, no napping. In other words, heads up!”

It Might Cure More Than Wrinkles
If you have excessive underarm or palm sweating or suffer from serious migraines, talk to your doctor about using Botox to cure these ills. It's been proven to diminish or stop excessive sweating, called hyperhidrosis, and to reduce the severity of migraines too—but don’t try tacking either treatment onto your cosmetic visit. You’ll need to book separate appointments. One quick tip: always take a quick peek at the box. “Botox meant for cosmetic purposes will say ‘Botox Cosmetic’ on the packaging,” says Dr. Khan. “Botox for medical purposes will say that on the package.”

A Happier Look Might Actually Improve Your Mood
If you’re prone to frowning, “eventually those muscles strengthen in that formation, which means it takes much effort to smile and look happy. When Botox relaxes those muscles, you look happier, which can really improve your mood and confidence,” says Dr. Gross.

Kristin Booker is a contributing writer on iVillage. Follow her on Twitter andGoogle+.

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Should You Try Botox? What We Wish We'd Known Before We Did

From wrinkles to migraines to happy faces, women share why they jumped on the Botox bandwagon

By Jeannette Moninger - June 26, 2013

It’s not just Real Housewives and Hollywood stars who want to stay youthful. In 2012, a record-setting 6.1 million Americans (94 percent of them women) received Botox injections. While some turn to the procedure to fight migraines or excessive sweating, the majority simply want to look younger. Here, women reveal the good, the bad and the ugly truth they learned from getting Botox.

Beware the Dog Face
“I loved how Botox softened my crow’s feet, so I tried it for frown lines between my brows. The effects were great — until I cried (and I cry often out of joy, sadness, hormonal reasons, you name it!). My inner eyebrows stayed the same, but the lower sections moved down giving me a basset hound appearance. I am an emotionally expressive person, so I will not be repeating that procedure.” —Stacey, age 45

It Can Cure Your 'Anger' Problem
“The deep crease between my eyebrows always made me look angry even when I was in great spirits. Without that line, I look so much more relaxed and youthful—happy even!” —Tina, age 48

Your Face Might Spasm
“When my Botox started to wear off, it felt like my forehead was having muscle spasms and contracting my eyebrows up toward my scalp. Thankfully, these spasms weren’t noticeable to others, but the sensation (which lasted for days) was very strange and really annoying.” —Sarah, age 44

You’ll Start Seeing Wrinkles Everywhere
“Since starting Botox, I’m very aware of how wrinkly other people’s foreheads are. But I would never tell my friends that.” —Ashlie, age 21

This Is Not the Time to Bargain Hunt
“I once experienced significant swelling after going to an inexperienced clinician. Ask your friends who they recommend and make sure the technician is well trained.” —Marisa, age 51

You Need to Be Realistic
“Botox isn’t a facelift-in-a-bottle. As a registered nurse who has both given and received injections, I find that most women’s expectations are too high. Botox is great at diminishing mild to moderate facial lines and wrinkles, but it won’t help saggy skin or deeply-etched lines. A good clinician should outline the changes you can realistically expect.” —Beth, age 52

It Really Can Prevent Migraines
“Getting Botox for migraines is like being stung repeatedly in the head. Still the pain is nothing compared to an actual migraine. My migraines have gone from about 15 a month to half that. It’s a win-win: Less pain and fewer wrinkles!” —Kari, age 44

It'll Stop Drippy Armpits
“My underarms used to drip before I started getting Botox for excessive sweating. The twice-yearly injections — about 20 per armpit — are not fun, but the payoff is sweet smelling.” —Robin, age 51

You Could Get Hooked
“At first I didn’t think I needed Botox. Now I’m scared to stop because I love what it has done for me. I feel younger, prettier and more confident” —Melissa, age 35

It's Not Just for Women With Wrinkles
“When deep creases started lining my forehead at age 27, I knew they’d only become deeper and more noticeable with age. I use Botox not necessarily to look younger, but to ensure that I won’t look older.” —Michelle, age 30

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