Showing posts with label reveals. Show all posts
Showing posts with label reveals. Show all posts

Monday, 19 August 2013

National audit of neonatal care reveals more positive experiences, but variations remain in key health outcomes for newborns, UK

Main Category: Pediatrics / Children's Health
Article Date: 19 Aug 2013 - 2:00 PDT Current ratings for:
National audit of neonatal care reveals more positive experiences, but variations remain in key health outcomes for newborns, UK
not yet ratednot yet rated

More than three quarters (79%) of the parents of babies in neonatal units are seen by senior healthcare professionals within 24 hours of admission and the majority of parents report positive experiences, but there is room for improvement in areas such as breastfeeding rates and levels of hypothermia in newborns, according to the 6th Annual National Neonatal Audit Programme 2012 (NNAP). The report is published today by the Royal College of Paediatrics and Child Health (RCPCH).

Commissioned by the Health Quality Improvement Partnership (HQIP), the audit measures neonatal units against a series of standards in order to assess if babies receive the right level and consistency of care across England and Wales.

The audit, which assessed 97% of English and Welsh units during 2012, found that:

79% of the parents of babies in neonatal units were seen by senior healthcare professionals within 24 hours of admission.57% of preterm babies born more than 7 weeks early were still receiving some of their mother's breast milk when discharged home. However just 33% of the babies were exclusively breast fed.90% of premature babies born 12 or more weeks early had their temperature recorded within an hour of birth - but 40% had a temperature less than 36.5oC.

Dr Mike Watkinson, RCPCH Project Lead for the National Neonatal Audit Programme, said:

"There is much to be positive about in this audit, with standards of care improving in many areas over the last five years. Data recording is also becoming more accurate and complete.

"But there is variation between units and neonatal networks in areas such as breastfeeding rates - something which we need to explore further to see how the moderately performing can be helped to match the best. It's also concerning that some trusts fail to record key data on every patient: this not only makes it a challenge to get a true national picture, but can under-estimate their own performance."

The audit also included a pilot of a confidential parent questionnaire, which showed that parents were satisfied with the level of involvement in their baby's care:

85% said they were 'always or nearly always' told about changes to their baby's condition or care79% said staff arranged their baby's care (such as weighing, bathing etc) to fit in with usual visiting times73% said doctors and nurses 'always or nearly always' involved them in discussions about their baby's care85% said they were 'definitely' involved as much as they wanted in the day-to-day care of their baby i.e. nappy changing

Dr Watkinson added:

"It's encouraging that the majority of parents in this pilot survey are happy with the standard of care their babies receive, but there are always improvements to make - and as we've identified with breastfeeding rates, more can be done to ensure health outcomes for these babies are even better."

In addition to the printed version of the audit, there will be an online resource highlighting examples of best practice which all units and the public can access.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our pediatrics / children's health section for the latest news on this subject. Please use one of the following formats to cite this article in your essay, paper or report:

MLA

Royal College of Paediatrics and Child Health. "National audit of neonatal care reveals more positive experiences, but variations remain in key health outcomes for newborns, UK." Medical News Today. MediLexicon, Intl., 19 Aug. 2013. Web.
19 Aug. 2013. APA
Royal College of Paediatrics and Child Health. (2013, August 19). "National audit of neonatal care reveals more positive experiences, but variations remain in key health outcomes for newborns, UK." Medical News Today. Retrieved from
http://www.medicalnewstoday.com/releases/264957.php.

Please note: If no author information is provided, the source is cited instead.


'National audit of neonatal care reveals more positive experiences, but variations remain in key health outcomes for newborns, UK'

Please note that we publish your name, but we do not publish your email address. It is only used to let you know when your message is published. We do not use it for any other purpose. Please see our privacy policy for more information.

If you write about specific medications or operations, please do not name health care professionals by name.

All opinions are moderated before being included (to stop spam). We reserve the right to amend opinions where we deem necessary.

Contact Our News Editors

For any corrections of factual information, or to contact the editors please use our feedback form.

Please send any medical news or health news press releases to:

Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.



View the original article here

Monday, 5 August 2013

Study reveals target for drug development for temporomandibular joint disorder (TMJD) - a chronic jaw pain disorder

Main Category: Dentistry
Also Included In: Pain / Anesthetics
Article Date: 05 Aug 2013 - 1:00 PDT Current ratings for:
Study reveals target for drug development for temporomandibular joint disorder (TMJD) - a chronic jaw pain disorder
not yet ratednot yet rated

Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or biting down, and lacks effective treatments.

In a study in mice, researchers at Duke Medicine identified a protein that is critical to TMJD pain, and could be a promising target for developing treatments for the disorder. Their findings are published in the August issue of the journal PAIN.

Aside from cases related to trauma, little is known about the root cause of TMJD. The researchers focused on TRPV4, an ion channel protein that allows calcium to rapidly enter cells, and its role in inflammation and pain associated with TMJD.

"TRPV4 is widely expressed in sensory neurons found in the trigeminal ganglion, which is responsible for all sensations of the head, face and their associated structures, such as teeth, the tongue and temporomandibular joint," said senior study author Wolfgang Liedtke, M.D., PhD, associate professor of neurology and neurobiology at Duke. "This pattern and the fact that TRPV4 has been found to be involved in response to mechanical stimulation made it a logical target to explore."

The researchers studied both normal mice and mice genetically engineered without the Trpv4 gene (which produces TRPV4 channel protein). They created inflammation in the temporomandibular joints of the mice, and then measured bite force exerted by the mice to assess jaw inflammation and pain, similar to how TMJD pain is gauged in human patients. Given that biting can be painful for those with TMJD, bite force lessens the more it hurts.

The mice without the Trpv4 gene had a smaller reduction in bite force - biting with almost full force - suggesting that they had less pain. In normal mice there was more TRPV4 expressed in trigeminal sensory neurons when inflammation was induced. The increase in TRPV4 corresponded with a greater reduction in bite force.

The researchers also administered a compound to normal mice that blocked TRPV4, and found that inhibiting TRPV4 also led to smaller reductions in bite force, similar to the effects of the mice engineered without the Trpv4 gene.

Surprisingly, the researchers found comparable bone erosion and inflammation in the jaw tissue across all mice, regardless whether the mice had TRPV4 or not.

"Remarkably, the damage is the same but not the pain," Liedtke said. "The mice that had the most TRPV4 appeared to have the most pain, but they all had similar evidence of temporomandibular joint inflammation and bone erosion in the jawbone as a consequence of the inflammation."

The results suggest that TRPV4 and its expression in trigeminal sensory neurons contribute to TMJD pain in mice. Given the lack of effective treatments for this chronic pain disorder, TRPV4 may be an attractive target for developing new therapies.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our dentistry section for the latest news on this subject.

In addition to Liedtke, Duke study authors include senior pain researcher Yong Chen, Ji Hee Hong, Suk Hee Lee, Puja K. Parekh and Carlene Moore of the Department of Neurology; Amy L. McNulty, Nicole E. Rothfusz and Farshid Guilak of the Department of Orthopaedic Surgery; Fan Wang of the Department of Cell Biology/Neurobiology; and Andrea B. Taylor of the Departments of Community and Family Medicine and Evolutionary Anthropology. Susan H. Williams of the Heritage College of Osteopathic Medicine at Ohio University and Robert W. Gereau IV of the Department of Anesthesiology at Washington University in St. Louis also contributed to this research.

The research was supported by the National Institutes of Health (DE018549, DE19440, DE19440S1, NS48602, AR048182 and DE018549-S); Duke Institute for Brain Sciences; Nicholas School of the Environment, Duke University; and Keimyung University School of Medicine in South Korea.

Duke University Medical Center

Please use one of the following formats to cite this article in your essay, paper or report:

MLA

Duke University Medical Center. "Study reveals target for drug development for temporomandibular joint disorder (TMJD) - a chronic jaw pain disorder." Medical News Today. MediLexicon, Intl., 5 Aug. 2013. Web.
5 Aug. 2013. APA
Duke University Medical Center. (2013, August 5). "Study reveals target for drug development for temporomandibular joint disorder (TMJD) - a chronic jaw pain disorder." Medical News Today. Retrieved from
http://www.medicalnewstoday.com/releases/264306.php.

Please note: If no author information is provided, the source is cited instead.


'Study reveals target for drug development for temporomandibular joint disorder (TMJD) - a chronic jaw pain disorder'

Please note that we publish your name, but we do not publish your email address. It is only used to let you know when your message is published. We do not use it for any other purpose. Please see our privacy policy for more information.

If you write about specific medications or operations, please do not name health care professionals by name.

All opinions are moderated before being included (to stop spam). We reserve the right to amend opinions where we deem necessary.

Contact Our News Editors

For any corrections of factual information, or to contact the editors please use our feedback form.

Please send any medical news or health news press releases to:

Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.



View the original article here