Clinique's NEW Dramatically Different Moisturizing Lotion+.

Have you heard? The iconic yellow lotion seen on more bathroom counters in America than any other has been reformulated to deliver even more dramatic results. Really, it is true. Introducing Clinique Dramatically Different Moisturizing Lotion+. Make note of the + (plus).

Why mess with a good thing? Clinique's famed moisturizer was already the #1 selling moisturizer in the United States, so why did they go and make it even more different? Well, times have changed and science had seen a lot of advancement in skin care. So Clinique took the latest ingredients and advancements to tweak the formula to make it even better.

Doing so was no easy task. It took 6 and a half years, 3 formulating dermatologists, 53 researchers, and 100 formul trials to get the new Dramatically Different Moisturizing Lotion+ just right.

See also: Clinique Dark Circle Eye Corrector

The mission was to provide barrier strength and to boost the moisturizing power of the lotion. The barrier repair complex is comprised with a blend of sunflower seed cake, barley extract and cucumber fruit extract that helps to strengthen the skin's barrier, imparting resilience ad resistance to environmental stresses. The new moisturizing ingredients include Hyaluronic Acid to help skin hold onto moisture for improved hydration; Glycerin to attract moisture to the skin; and Urea, which is a naturally occurring component in the products of the skin's own moisturizing factor that helps to mimic that function.

Dramatically Different Moisturizing Lotion+ was tested on 1,600 people of different ethnicities across 5 countries. Users saw:

50% improvement in moisture for all day hydration without an extra drop of oil54% improvement in skin's barrier strength in eight weeks without changing the famously silky texture.

I can attest to both of those statements. The new Dramatically Different Moisturizing Lotion+ formula looks the same, feels the same, and still absorbs very rapidly. This formula keeps my skin feeling hydrating and and glowing all day.

Look for Dramatically Different Moisturizing Lotion+ on Clinique counters and online at clinique.com now. It retails for $26.00 for 4.2 oz.

A press sample of the product featured may have been provided by brand or brand representative for editorial consideration. All opinions are my own. Affiliate links may have also been used in the post. Please see disclosure policy for complete information.

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Different brain organization identified in autistic children who excel at math

Main Category: Autism
Also Included In: Psychology / Psychiatry
Article Date: 20 Aug 2013 - 0:00 PDT Current ratings for:
Different brain organization identified in autistic children who excel at math

Children with autism and average IQs consistently demonstrated superior math skills compared with nonautistic children in the same IQ range, according to a study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

"There appears to be a unique pattern of brain organization that underlies superior problem-solving abilities in children with autism," said Vinod Menon, PhD, professor of psychiatry and behavioral sciences and a member of the Child Health Research Institute at Packard Children's.

The autistic children's enhanced math abilities were tied to patterns of activation in a particular area of their brains - an area normally associated with recognizing faces and visual objects.

Menon is senior author of the study, published online Aug. 17 in Biological Psychiatry. Postdoctoral scholar Teresa Iuculano, PhD, is the lead author.

Children with autism have difficulty with social interactions, especially interpreting nonverbal cues in face-to-face conversations. They often engage in repetitive behaviors and have a restricted range of interests.

But in addition to such deficits, children with autism sometimes exhibit exceptional skills or talents, known as savant abilities. For example, some can instantly recall the day of the week of any calendar date within a particular range of years - for example, that May 21, 1982, was a Friday. And some display superior mathematical skills.

"Remembering calendar dates is probably not going to help you with academic and professional success," Menon said. "But being able to solve numerical problems and developing good mathematical skills could make a big difference in the life of a child with autism."

The idea that people with autism could employ such skills in jobs, and get satisfaction from doing so, has been gaining ground in recent years.

The participants in the study were 36 children, ages 7 to 12. Half had been diagnosed with autism. The other half was the control group. Each group had 14 boys and four girls. (Autism disproportionately affects boys.) All participants had IQs in the normal range and showed normal verbal and reading skills on standardized tests administered as part of the recruitment process for the study. But on the standardized math tests that were administered, the children with autism outperformed children in the control group.

After the math test, researchers interviewed the children to assess which types of problem-solving strategies each had used: Simply remembering an answer they already knew; counting on their fingers or in their heads; or breaking the problem down into components - a comparatively sophisticated method called decomposition. The children with autism displayed greater use of decomposition strategies, suggesting that more analytic strategies, rather than rote memory, were the source of their enhanced abilities.

Then, the children worked on solving math problems while their brain activity was measured in an MRI scanner, in which they had to lie down and remain still. The brain scans of the autistic children revealed an unusual pattern of activity in the ventral temporal occipital cortex, an area specialized for processing visual objects, including faces.

"Our findings suggest that altered patterns of brain organization in areas typically devoted to face processing may underlie the ability of children with autism to develop specialized skills in numerical problem solving," Iuculano said.

Menon added that previous research "has focused almost exclusively on weaknesses in children with autism. Our study supports the idea that the atypical brain development in autism can lead, not just to deficits, but also to some remarkable cognitive strengths. We think this can be reassuring to parents."

The research team is now gathering data from a larger group of children with autism to learn more about individual differences in their mathematical abilities. Menon emphasized that not all children with autism have superior math abilities, and that understanding the neural basis of variations in problem-solving abilities is an important topic for future research.

"These findings not only empirically confirm that high-functioning children with autism have especially strong number-problem-solving abilities, but show that this cognitive strength in math is based on different patterns of functional brain organization," said Carl Feinstein, MD, director of the Center for Autism and Related Disorders at Packard Children's and professor of psychiatry and behavioral sciences at the School of Medicine. He was not involved in the study.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our autism section for the latest news on this subject.

Other Stanford co-authors are postdoctoral scholars Miriam Rosenberg-Lee, PhD, and Kaustubh Supekar, PhD; social science research assistants Charles Lynch and Amirah Khouzam; Jennifer Phillips, PhD, clinical associate professor of psychiatry and behavioral sciences and a clinical psychologist at Packard Children's; and Lucina Uddin, PhD, instructor in psychiatry and behavioral sciences.

The study was funded by grants from the Singer Foundation, the Stanford Institute for Neuro-Innovation & Translational Neurosciences, and the National Institutes of Health (grant MH084164).

Stanford University Medical Center

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Taste preference changes in different life stages of rats

Main Category: Seniors / Aging
Also Included In: Nutrition / Diet
Article Date: 02 Aug 2013 - 0:00 PDT Current ratings for:
Taste preference changes in different life stages of rats

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, found that aging elicits changes in taste preferences and that such changes appear to be independent of taste nerve activity.

In humans and animals aging decreases dietary and energy requirements and it is generally believed that reduced consumption is related to alterations in taste preference. However, the mechanisms underlying an age-induced shift in taste preference remain unclear. Thus, the researchers investigated differences in fluid intake and taste nerve responses across different age groups of rats.

The researchers initially measured the intake of sweet, salty, umami, sour or bitter taste solutions in 5 age groups; juvenile, young-adult, adult, middle-aged and old-aged male rats. The result showed that older animals exhibit a decreased preference for sweet and umami taste and a reduced aversion to bitter taste.

Additional behavioral studies examined whether aging alters taste thresholds by measuring the consumption of simultaneously presented high- and low-concentrated taste solutions. This work revealed that taste sensitivity is lower in older rats.

To elucidate the neural mechanisms of such age-related changes in taste preference and sensitivity, electrophysiological experiments examined taste response characteristics of chorda tympani nerves. These nerves mediate gustatory information from the tongue to the brainstem. The researchers observed no significant differences in activity of the chorda tympani nerves by taste stimuli across the different age groups.

Overall, these behavioral and electrophysiological studies demonstrate that age-related changes in taste preference and sensitivity are independent of the peripheral gustatory system.

The lead author of the study, Chizuko Inui-Yamamoto, Ph.D. states, "To our knowledge, this is the first report demonstrating a reduced aversion to bitter taste in aged rats." She comments, "We had expected that these changes were due to the peripheral taste system." However, differences in electrophysiological recording of taste responses of the chorda tympani nerves across age groups were not observed. "Our studies showed that aging elicited no changes in transmission of taste information from the tongue to the central nervous system. Thus, our future work will investigate the role of the central nervous system in mediating age-induced changes in taste preference", says Inui-Yamamoto.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our seniors / aging section for the latest news on this subject.

This work was supported by JSPS KAKENHI Grant-in-Aid for Young Scientists (B), Grant Number 23792136.

Lead Author: Chizuko Inui-Yamamoto, Dept. of Oral Anatomy, Osaka Dental University

Co-Authors: Takashi Yamamoto, Katsura Ueda, Michiko Nakatsuka, Chunying An, Shunji Kumabe, Yasutomo Iwai

Society for the Study of Ingestive Behavior

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Placebo effects of different therapies not identical

Main Category: Clinical Trials / Drug Trials
Also Included In: Psychology / Psychiatry
Article Date: 31 Jul 2013 - 14:00 PDT Current ratings for:
Placebo effects of different therapies not identical

Not all placebos are equal, and patients who respond to one placebo don't always respond to others, according to research published July 31 in the open access journal PLOS ONE by Jian Kong from Massachusetts General Hospital, Harvard Medical School and colleagues from other institutions.

The researchers tested the analgesic effects of genuine acupuncture, sham acupuncture and a placebo pill on healthy participants' pain sensitivity. Participants were not told what treatment they were receiving, but were informed that the pill was Tylenol, a well-known painkiller and different schools of acupuncture: electroacupuncture and manual acupuncture (sham acupuncture). A control group received no treatment at all. Shortly before and after each treatment, a warm electrode was placed on participants' forearms and the temperature gradually increased. They were asked to indicate when the heat first became painful and when it became too hot to tolerate to identify pain thresholds and tolerance.

No significant associations were found between participants' responses to the different treatments, suggesting that none of these individuals could be identified as placebo 'responders' or 'non-responders'. However, participants' expectations that the treatment would help relieve pain correlated with their pain thresholds and tolerance.

According to the authors, these and other parameters in their study suggest that responses to a placebo depend on diverse factors including the route of administration (pills or acupuncture), environmental cues, and learning based on verbal suggestions or conditioning. Kong adds, "It implies that placebo responses may not be dependent on stable individual traits but rather are more a characteristic of the circumstances of individuals or a combination of both trait and state."

In addition, they also found subjects' responses to sham acupuncture correlated significantly with their response to genuine acupuncture. This suggest that people who responded to genuine acupuncture were significantly more likely to experience pain relief from sham acupuncture, but the authors clarify that this does not indicate the two are the same. Instead, they suggest that acupuncture may have non-specific pain-relieving effects that may contribute to this observation.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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Are All Placebo Effects Equal? Placebo Pills, Sham Acupuncture, Cue Conditioning and Their Association. PLoS ONE 8(7): e67485. doi:10.1371/journal.pone.0067485

Authors: Kong J, Spaeth R, Cook A, Kirsch I, Claggett B, et al.

This work was supported by KO1AT003883 (NCCAM), R21AT004497 (NCCAM), R03AT218317 (NIDA), and R01AT006364 (NCCAM) to Jian Kong; R01AT005280 (NCCAM) to Randy Gollub; K24AT004095 (NCCAM) to Ted Kaptchuk; K24MH094614 (NIMH) to Jordan W. Smoller, and P01 AT006663 (NCCAM) to Bruce Rosen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

PLoS ONE

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