Digital visualization in 3-D of cervical nerves in a healthy person

Main Category: Neurology / Neuroscience
Also Included In: Radiology / Nuclear Medicine
Article Date: 15 Aug 2013 - 0:00 PDT Current ratings for:
Digital visualization in 3-D of cervical nerves in a healthy person

High-resolution multilayer X-ray computer tomography and 3.0T superconducting magnetic resonance myelography are known to obtain a more complete and continuous two-dimensional original data.

Three-dimensional reconstruction nerve models are classically obtained from two-dimensional images of "visible human" frozen sections. However, because of the flexibility of nerve tissues and small color differences compared with surrounding tissues, the integrity and validity of nerve tissues can be impaired during milling.

Jiaming Fu and colleagues from the 98 Hospital of Chinese PLA successfully developed a three-dimensional digital visualization model of healthy human cervical nerves, which overcomes the disadvantages of milling, avoids data loss, and exhibits a realistic appearance and three-dimensional image. Furthermore, vivid images from various angles can be observed due to minimal pattern distortion. This model revealed the morphology, distribution, and spatial relations of the major nerves of the neck, and provided three-dimensional morphological data for anatomical teaching and morphological observation of regenerated nerves, nerve block anesthesia, and surgery.

These results are published in Neural Regeneration Research (Vol. 8, No. 20, 2013).

Article: " A three-dimensional digital visualization model of cervical nerves in a healthy person," by Jiaming Cao1, Dong Fu2, Sen Li3 (1 Department of Anesthesiology, the 98 Hospital of Chinese PLA, Huzhou 313000, Zhejiang Province, China; 2 Department of Surgery, Hospital of 8691 People's Armed Police Force, Huzhou 313000, Zhejiang Province, China; 3 Department of Spinal Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China)

doi:10.3969/j.issn.1673-5374.2013.20.001; 2013;8(20):1829-1836.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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Repairing injured sciatic nerves

Main Category: Neurology / Neuroscience
Article Date: 15 Aug 2013 - 0:00 PDT Current ratings for:
Repairing injured sciatic nerves

The conventional method for repair of peripheral nerve injury is autogenous nerve grafting, but sources of autogenous nerve are limited. Furthermore, neurological deficits in the donor site and painful neuroma can occur following surgery.

The use of allogeneic nerve grafts is limited because of host immune rejection. As reported, tensile stress and tensile strain directly affect the quality of nerve regeneration after bridging nerve defects by poly(lactic-co-glycolic acid) conduit transplantation and autogenous nerve grafting for sciatic nerve injury.

A new study published in the Neural Regeneration Research (Vol. 8, No. 21, 2013) showed that, following poly(lactic-co-glycolic acid) conduit transplantation for sciatic nerve repair, the maximum tensile load, maximum stress, elastic limit load and elastic limit stress all increased compared with autogenous nerve grafts, but elastic limit strain and maximum strain decreased. Moreover, the tendencies of stress-strain curves of sciatic nerves were similar after transplantation of poly(lactic-co-glycolic acid) conduits or autogenous nerve grafts. These findings indicate that poly(lactic-co-glycolic acid) conduits are suitable for sciatic nerve injury repair.

Article: " Poly(lactic-co-glycolic acid) conduit for repair of injured sciatic nerve: a mechanical analysis," by Tao Yu1, Changfu Zhao1, Peng Li2, Guangyao Liu1, Min Luo1 (1 Department of Orthopedics, China-Japan Union Hospital, Jilin University, Changchun 130031, Jilin Province, China; 2 Department of Engineering Mechanics, Nanling Campus of Jilin University, Changchun 130022, Jilin Province, China)

Yu T, Zhao CF, Li P, Liu GY, Luo M. Poly(lactic-co-glycolic acid) conduit for repair of injured sciatic nerve: a mechanical analysis. Neural Regen Res. 2013;8(21):1966-1973. doi:10.3969/j.issn.1673-5374.2013.21.005

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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Research, Neural Regeneration. "Repairing injured sciatic nerves." Medical News Today. MediLexicon, Intl., 15 Aug. 2013. Web.
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'Repairing injured sciatic nerves'

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View the original article here