Showing posts with label Where. Show all posts
Showing posts with label Where. Show all posts

Saturday, 28 September 2013

Can foundation trusts survive and where do their loyalties lie?

mind the gap A gap in areas lies between the governors and the non-executive directors of foundation trusts, writes David Walker. Photograph: Martin Argles for the Guardian

The polite word is 'hybrid'. The less polite is 'incoherent'. Either way, NHS foundation trusts are based on two contradictory visions of how they should operate and who should call the shots, and the 2012 Health Act is increasing the tension between them.

Ten years ago, Labour had a wacky idea. Instead of making primary care – the part of the NHS closest to people — more accountable, it would inject democracy into the providers of healthcare in the hospitals, ambulance, and mental health services. They, not the GPs, would have elections. The notion is now looking odder and odder, partly because of the competitive pressures stoked by the Cameron coalition's health act and partly because it's commissioning that needs accountability most.

No wonder, then, you start to overhear backstairs conversations asking whether the foundation trust (FT) model can survive. One half of the hybrid is the community, the people using the service, staff and patients themselves and it is they who elect FT governors. Alan Milburn, the Labour health secretary, dreamily talked of mutualism – but then set up a regulator, Monitor, to enforce strict business principles on FTs.

So the other half of the FT model is hardheaded commerce, profit and loss and earnings before interest, depreciation and amortisation. FTs are meant to behave like businesses, going for growth and profit. How are governors meant to square their desire for a local service with the FT board's concern to balance the books by closing a clinic here or a much-loved ward over there?

Democracy and profitability may be fated to war. Paul Hackett, director of the Smith Institute, notes 'all public institutions face tensions between representation and effectiveness', including school governing bodies and councils themselves. Smith, a centre-left thinktank, has just teamed up with the Association of Chartered Certified Accountants to paint a picture of FT governance.

It's healthier than might have been thought, confirming surveys by Monitor. Total numbers involved have actually been growing though FT governors tend to be older and retired; half their elections are not contested. Still, many thousands of people, embedded in local areas across England (the experiment did not extend to the rest of the UK), contribute vast amounts of time and energy to their mental health, community and hospital services through membership of a trust.

The Smith report warns against generalisation – FTs vary widely in their levels of activism, and in how close governors get to board decision-making, especially in matters of finance. A yawning gap in many areas lies between the governors and the non-executive directors, who are not representative of the area but on the board to ensure trusts operate efficiently and effectively.

The Tories, embarrassed at the complete absence of accountability from their original ideas for clinical commissioning by GPs, inserted more powers for FT governors in the 2012 act; they now shadow many of the decisions taken by FT boards, without being paid and without the support apparatus boards tend to have.

Ahead lie problems. Governors are the public and want to operate in the open.

But how can FTs compete with private providers if their cost schedules and profit assumptions are declared in advance? Virgin of course has no governors. Its shareholders are institutional investors who play no part in executive decision taking unless profits go down. What if governors, responsive to staff and patients, opt for a lower rate of return than the board, mindful of competitive pressures? Who should have the last word?

If governors represent one area, what role should they play if an FT acquires healthcare responsibility in another area and the notion of 'local' gets stretched? In London, the executives of better-performing FTs are supposed to lend a hand to trusts in difficulty (most of them still in the notional pipeline to becoming FTs): governors might object to 'their' managers being distracted from serving the local area.

Do governors have any role in bidding for contracts from clinical commissioners? Or from councils? Now that public health has shifted to councils, some FTs are fighting for contracts from the town hall: is the local authority or the FT governing council more 'representative' of an area? The better FT governing councils are those that include elected councillors, but where now do their primary loyalties lie?

David Walker is a non-executive director of a foundation trust; the views expressed here are his own

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Tuesday, 24 September 2013

Where next for public health? – Live discussion

Picture of someone smoking and drinking Public health became a local authority responsibility in April, with councils in control of public health issues such as tackling smoking. Photograph: Alamy

The transfer of public health responsibility to local authorities this April marked a turning point in how local health issues are tackled. But, five months on, what has been learned, and where do we go from here?

Richard Humphries, assistant director of policy at the King's Fund, recently commented on how the relationship between the NHS and local government has changed. He said:

Our latest research is encouraging. Relationships between councils and clinical commissioning groups are generally good, and getting better. The new health and wellbeing boards are investing time in developing relationships and joint strategies are in place.

Questions remain, he said, including how far councils will support NHS partners in delivering local services and whether austerity will compel change or damage the local relationships.

Humphries said: "This will play out differently; places with a tradition of good local relationships have a better chance of weathering the financial storm." With this in mind what do councils need to do to ensure that they build a strong relationship in the future?

• What has been learned from experiences so far?

• What are the areas of highest priority?

• How can councils use the powers available to them to really make a difference?

• What approach should councils adopt?

• Do councils need more powers?

Join us 25 September from 12pm-2pm to discuss, or leave your comments and questions now.

Expert panel:
Edward Davie is a Lambeth councillor and chair of Lambeth council's health and adult social services scrutiny committee.

Jonathan McShane sits on the Local Government Association community wellbeing board, leading on sexual health and public health services. He is a councillor in Hackney, east London.

Steven Howell is senior policy and communications officer at local government thinktank Localis.

Mary Black is a medical doctor, a consultant in public health and director of public health designate for the London borough of Havering.

Helen Walters leads the health team in the mayor of London's office and works for Public Health England. She is a public health specialist with experience of working in local government, the NHS and as a GP

Liz Saunders is associate director of public health at Surrey county council.

Oswin Baker founded Rockpool Research Associates, a network of researchers with expertise in local government and healthcare.

Tom Scanlon has been director of public health in Brighton and Hove since 2002. He also practises as a sessional GP and is an Honorary Senior Research Associate at University College London Centre for International Health and Development.

Janet Atherton is president at Association of Directors of Public Health . She has been a local director of public health since 1998, first in Wirral and then Sefton in Merseyside.

Anne Bowers is an associate director at healthcare consultancy PPL.

Anna Quigley leads public sector health research at Ipsos Mori, including research with the general public and people within the health sector about public health issues.

• What do you think? Email sarah.marsh@theguardian.com if you want to contribute an article to this debate.

Not already a member? Join us now for more comment, analysis and the latest job opportunities in local government.


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Friday, 16 August 2013

Where in the body immune cells reach maturity is important for their later function

Main Category: Immune System / Vaccines
Article Date: 16 Aug 2013 - 0:00 PDT Current ratings for:
Where in the body immune cells reach maturity is important for their later function
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Regulatory T cells (or "Tregs" for short) play a central role in the human immune system: They guide all of the other immune cells and make sure they are tolerant of the body's own cells and harmless foreign substances. How Tregs become Tregs in the first place has been only incompletely understood - until now. Scientists at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, along with their colleagues at the Hannover Medical School (MHH) have recently gleaned important new insights into the workings of these cells. As it turns out, origin is key - greater numbers of Tregs are produced within certain lymph nodes than in others. The researchers are now publishing their insights in the scientific journal Mucosal Immunology.

Without regulatory T cells, the human defence system would not work properly. Defender cells would be fiercely fighting off even harmless foreign substances like the parts of certain kinds of food, for example, as the immune system would simply not be "tolerant" towards these harmless substances. This tolerance is mediated through the Tregs - they are "tolerogenic."

They instruct other immune cells as to which intruders really do need to be fought off and which ones do not pose a threat. However, even regulatory T cells have to first acquire this unique skill. What we have known for some time now is that they receive their "training" inside lymph nodes. "Lymph nodes are basically the immune system's meeting points if you will," says Prof. Jochen Hühn, Head of Experimental Immunology at the HZI. "Here, different types of immune cells meet up and also encounter antigen." An antigen is a structure the immune system is able to recognize like component parts of pathogens or foods.

The researchers compared the development of murine T cells obtained from lymph nodes from various locations in the body, like the liver, intestine, and skin. In the process, they learned that more Tregs capable of teaching other cells to be tolerant of food antigens are made inside lymph nodes of the liver and intestine - a property the lymph nodes maintained even when they were transplanted to the skin. Conversely, skin lymph nodes did not become more tolerogenic if transplanted to the intestine. The HZI scientists made these discoveries together with their colleagues from Prof. Oliver Papst's team at the MHH Institute of Immunology.

Based on their observations, the scientists deduced that lymph node location influences the maturation process of the cells they contain. "The cells retained their original skills for weeks following the transplant," says Dr. Sascha Cording, one of the study's first authors. "You might say lymph nodes have something like a location-specific memory."

And this in spite of the fact that all the various types of blood cells within a lymph node, including the immune cells, are constantly replaced, which means the lymph nodes' location memory must be encoded somewhere in its stroma.

Additional experiments allowed the scientists to probe just how lymph nodes obtain their memory: Following birth, both the supply of vitamin A and the intestinal bacterial microflora figure prominently into this process. Without these two influencing factors, the lymph nodes simply forget about their origin and lose their tolerogenic properties.

These findings about lymph node imprinting apply to humans as well: An inadequate supply of vitamin A after birth or meddling with the baby's developing microflora through administration of antibiotics can interfere with the lymph nodes' long-term memory. "At what age this process happens in humans we cannot as of yet pinpoint with any certainty," says Hühn. "Whether we're talking about the first few days, weeks, or months even, is difficult to surmise." The next step will be identifying the potential repercussions interfering with early imprinting of the immune system. Down the line, things like food allergies or autoimmune diseases might be the result.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our immune system / vaccines section for the latest news on this subject.

The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodes

Sascha Cording, Benjamin Wahl, Devesha Kulkarni, Himprya Chopra, Jörn Pezoldt, Manuela Buettner, Annegret Dummer, Usri Hadis, Markus Heimesaat, Stefan Bereswill, Christine Falk, Ulrike Bode, Alf Hamann, Diana Fleissner, Jochen Huehn, Oliver Pabst

Mucosal Immunology, 2013, DOI: 10.1038/mi.2013.54

Helmholtz Centre for Infection Research

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