Mascara Monday: Avon Mega Effects Mascara.

This is the most differently shaped mascara wand I have ever seen. I was sort of afraid to even try it because it looks so intense. Have you seen the new Avon Mega Effects Mascara?

This secret to this mascara is obviously the multi-dimensional brush and straight forward application process. Now that you have seen it, let's take a look at it and how it works.

First, I didn't really know where to open, but quickly figured out to simply lift off the red cap. Inside, I see what looks like a paint brush in a cover. I pulled straight up (hard), and out came the little paint brush looking device.

This is no paint brush I must say. It is actually a comb that is curved a bit, just like the shape of the eye. On the comb are various lengths of soft plastic bristles that are crisscrossed on top of the comb. In the comb lies a ton of mascara. It actually holds 40% more mascara than an average mascara brush, making it easier to get the formula into lashes.

The handle is hinged and moves. I played with it to find where it exactly it felt most comfortable close to my eye. I did find it easy to hols once I had it correctly positioned, close to my eye.

See also: Affordable Beauty Solutions from Avon

The application process took some getting used too. I am so used to holding a wand horizontally over my lashes. To be honest though, by applying straight on, it is easier to see and get to each and every lash. It is especially great for bottom lashes, in my opinion.

The formula itself, was nice, and I found that I just need two coats to get a nice defined look with a lot of volume. Because you do get a lot of mascara on the brush, it does need a minute or two to dry between coats. I also don't suggest over using, because three or more coats can start to get clumpy. The mascara seems to last most of the day and I did not experience any smudging or flaking. With practice, this mascara definitely gets the job done.

Avon Mega Effects Mascara sells for $10.00 and is available now through your Avon representative or avon.com.

A press sample of the product featured may have been provided by brand or brand representative for editorial consideration. All opinions are my own. Affiliate links may have also been used in the post. Please see disclosure policy for complete information.

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Copyright © 2001 - 2013 Beautiful Makeup Search.

View the original article here

Mascara Monday: Avon Mega Effects Mascara.

This is the most differently shaped mascara wand I have ever seen. I was sort of afraid to even try it because it looks so intense. Have you seen the new Avon Mega Effects Mascara?

This secret to this mascara is obviously the multi-dimensional brush and straight forward application process. Now that you have seen it, let's take a look at it and how it works.

First, I didn't really know where to open, but quickly figured out to simply lift off the red cap. Inside, I see what looks like a paint brush in a cover. I pulled straight up (hard), and out came the little paint brush looking device.

This is no paint brush I must say. It is actually a comb that is curved a bit, just like the shape of the eye. On the comb are various lengths of soft plastic bristles that are crisscrossed on top of the comb. In the comb lies a ton of mascara. It actually holds 40% more mascara than an average mascara brush, making it easier to get the formula into lashes.

The handle is hinged and moves. I played with it to find where it exactly it felt most comfortable close to my eye. I did find it easy to hols once I had it correctly positioned, close to my eye.

See also: Affordable Beauty Solutions from Avon

The application process took some getting used too. I am so used to holding a wand horizontally over my lashes. To be honest though, by applying straight on, it is easier to see and get to each and every lash. It is especially great for bottom lashes, in my opinion.

The formula itself, was nice, and I found that I just need two coats to get a nice defined look with a lot of volume. Because you do get a lot of mascara on the brush, it does need a minute or two to dry between coats. I also don't suggest over using, because three or more coats can start to get clumpy. The mascara seems to last most of the day and I did not experience any smudging or flaking. With practice, this mascara definitely gets the job done.

Avon Mega Effects Mascara sells for $10.00 and is available now through your Avon representative or avon.com.

A press sample of the product featured may have been provided by brand or brand representative for editorial consideration. All opinions are my own. Affiliate links may have also been used in the post. Please see disclosure policy for complete information.

Copyright © 2001 - 2013 Beautiful Makeup Search.

View the original article here

Mascara Monday: Avon Mega Effects Mascara.

This is the most differently shaped mascara wand I have ever seen. I was sort of afraid to even try it because it looks so intense. Have you seen the new Avon Mega Effects Mascara?

This secret to this mascara is obviously the multi-dimensional brush and straight forward application process. Now that you have seen it, let's take a look at it and how it works.

First, I didn't really know where to open, but quickly figured out to simply lift off the red cap. Inside, I see what looks like a paint brush in a cover. I pulled straight up (hard), and out came the little paint brush looking device.

This is no paint brush I must say. It is actually a comb that is curved a bit, just like the shape of the eye. On the comb are various lengths of soft plastic bristles that are crisscrossed on top of the comb. In the comb lies a ton of mascara. It actually holds 40% more mascara than an average mascara brush, making it easier to get the formula into lashes.

The handle is hinged and moves. I played with it to find where it exactly it felt most comfortable close to my eye. I did find it easy to hols once I had it correctly positioned, close to my eye.

See also: Affordable Beauty Solutions from Avon

The application process took some getting used too. I am so used to holding a wand horizontally over my lashes. To be honest though, by applying straight on, it is easier to see and get to each and every lash. It is especially great for bottom lashes, in my opinion.

The formula itself, was nice, and I found that I just need two coats to get a nice defined look with a lot of volume. Because you do get a lot of mascara on the brush, it does need a minute or two to dry between coats. I also don't suggest over using, because three or more coats can start to get clumpy. The mascara seems to last most of the day and I did not experience any smudging or flaking. With practice, this mascara definitely gets the job done.

Avon Mega Effects Mascara sells for $10.00 and is available now through your Avon representative or avon.com.

A press sample of the product featured may have been provided by brand or brand representative for editorial consideration. All opinions are my own. Affiliate links may have also been used in the post. Please see disclosure policy for complete information.

Copyright © 2001 - 2013 Beautiful Makeup Search.

View the original article here

Placebo effects of different therapies not identical

Main Category: Clinical Trials / Drug Trials
Also Included In: Psychology / Psychiatry
Article Date: 31 Jul 2013 - 14:00 PDT Current ratings for:
Placebo effects of different therapies not identical

Not all placebos are equal, and patients who respond to one placebo don't always respond to others, according to research published July 31 in the open access journal PLOS ONE by Jian Kong from Massachusetts General Hospital, Harvard Medical School and colleagues from other institutions.

The researchers tested the analgesic effects of genuine acupuncture, sham acupuncture and a placebo pill on healthy participants' pain sensitivity. Participants were not told what treatment they were receiving, but were informed that the pill was Tylenol, a well-known painkiller and different schools of acupuncture: electroacupuncture and manual acupuncture (sham acupuncture). A control group received no treatment at all. Shortly before and after each treatment, a warm electrode was placed on participants' forearms and the temperature gradually increased. They were asked to indicate when the heat first became painful and when it became too hot to tolerate to identify pain thresholds and tolerance.

No significant associations were found between participants' responses to the different treatments, suggesting that none of these individuals could be identified as placebo 'responders' or 'non-responders'. However, participants' expectations that the treatment would help relieve pain correlated with their pain thresholds and tolerance.

According to the authors, these and other parameters in their study suggest that responses to a placebo depend on diverse factors including the route of administration (pills or acupuncture), environmental cues, and learning based on verbal suggestions or conditioning. Kong adds, "It implies that placebo responses may not be dependent on stable individual traits but rather are more a characteristic of the circumstances of individuals or a combination of both trait and state."

In addition, they also found subjects' responses to sham acupuncture correlated significantly with their response to genuine acupuncture. This suggest that people who responded to genuine acupuncture were significantly more likely to experience pain relief from sham acupuncture, but the authors clarify that this does not indicate the two are the same. Instead, they suggest that acupuncture may have non-specific pain-relieving effects that may contribute to this observation.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our clinical trials / drug trials section for the latest news on this subject.

Are All Placebo Effects Equal? Placebo Pills, Sham Acupuncture, Cue Conditioning and Their Association. PLoS ONE 8(7): e67485. doi:10.1371/journal.pone.0067485

Authors: Kong J, Spaeth R, Cook A, Kirsch I, Claggett B, et al.

This work was supported by KO1AT003883 (NCCAM), R21AT004497 (NCCAM), R03AT218317 (NIDA), and R01AT006364 (NCCAM) to Jian Kong; R01AT005280 (NCCAM) to Randy Gollub; K24AT004095 (NCCAM) to Ted Kaptchuk; K24MH094614 (NIMH) to Jordan W. Smoller, and P01 AT006663 (NCCAM) to Bruce Rosen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

PLoS ONE

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Saliva study of cell phone effects

Editor's Choice
Main Category: Cancer / Oncology
Also Included In: Public Health
Article Date: 31 Jul 2013 - 7:00 PDT Current ratings for:
Saliva study of cell phone effects
Frequent cell phone use may be linked to cancer, suggests a study from researchers at Tel Aviv University, led by Dr. Yaniv Hamzany.

The study paper poses the question, Is human saliva an indicator of the adverse health effects of using mobile phones? The authors decided to turn to saliva to test a hypothesis that the salivary gland would give clues to cell phone risks - the gland sits in close proximity to a cell phone when in use.

The researchers examined 20 participants who had been using a mobile phone for an average of 12.5 years and for between 8 and 100 hours a month. The participants' saliva was then compared with that of a control group - deaf patients who did not use a cell phone, or who only used a phone to text.

Salivary characteristics measured by the researchers included:

SecretionOxidative damage indicesFlow rateComposition.

Results showed that the cell phone users had higher oxidative stress in their saliva. This is a mechanism that damages cells by developing toxic peroxide and free radicals. Oxidative stress is also a risk factor for cancer.

"This suggests that there is considerable oxidative stress on the tissue and glands which are close to the cell phone in use," says Dr. Yaniv Hamzany - damage that could cause tumors to develop.

This study only involved 20 participants and cannot show a clear cause-and-effect relationship between using a cell phone and cancer, but it does contribute to evidence that using cell phones may cause harm.

The researchers say:

"Increasing use of mobile phones creates growing concerns regarding harmful effects of radiofrequency nonionizing electromagnetic radiation on human tissues located close to the ear, where phones are commonly held for long periods of time."

Dr. Yaniv Hamzany notes that future research may involve analyzing a subject's saliva before and after using a cell phone - to see if there is an immediate measurable effect.

A charity in the UK has recently announced a partnership with a software agency to develop a mobile game through which the general public can analyze cancer data while playing. See our news story: Cell phone game joins fight against cancer. So, we can fight cancer with our mobile phones, as long as - this most recent research may be suggesting - we do not regularly hold the phones to our ears for long periods.

Written by Marie Ellis

Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today Visit our cancer / oncology section for the latest news on this subject. Please use one of the following formats to cite this article in your essay, paper or report:

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Identification of key target responsible for triggering detrimental effects in brain trauma

Main Category: Neurology / Neuroscience
Also Included In: Stroke
Article Date: 29 Jul 2013 - 1:00 PDT Current ratings for:
Identification of key target responsible for triggering detrimental effects in brain trauma

Researchers studying a type of cell found in the trillions in our brain have made an important discovery as to how it responds to brain injury and disease such as stroke. A University of Bristol team has identified proteins which trigger the processes that underlie how astrocyte cells respond to neurological trauma.

The star-shaped astrocytes, which outnumber neurons in humans, are a type of glial cell that comprise one of two main categories of cell found in the brain along with neurons. The cells, which have branched extensions that reach synapses (the connections between neurons) blood vessels, and neighbouring astrocytes, play a pivotal role in almost all aspects of brain function by supplying physical and nutritional support for neurons. They also contribute to the communication between neurons and the response to injury.

However, the cells are also known to trigger both beneficial and detrimental effects in response to neurological trauma. When the brain is subjected to injury or disease, the cells react in a number of ways, including a change in shape. In severe cases, the altered cells form a scar, which is thought to have beneficial, as well as detrimental effects by allowing prompt repair of the blood-brain barrier, and limiting cell death, but also impairing the regeneration of nerve fibres and the effective incorporation of neuronal grafts - where additional neuronal cells are added to the injured site.

The cells change shape via the regulation of a structural component of the cell called the actin cytoskeleton, which is made up of filaments that shrink and grow to physically manoeuvre parts of the cell. In the lab, the team cultured astrocytes in a dish and were able to make them change shape by chemically or genetically manipulating proteins that control actin, and also by mimicking the environment that the cells would be exposed to during a stroke.

By doing so the team found that very dramatic changes in cell shape were caused by controlling the actin cytoskeleton in the in vitro stroke model. The team also identified additional protein molecules that control this process, suggesting that a complex mechanism is involved.

Dr Jonathan Hanley from the University's School of Biochemistry said: "Our findings are crucial to our understanding of how the brain responds to many disorders that affect millions of people every year. Until now, the details of the actin-based mechanisms that control astrocyte morphology were unknown, so we anticipate that our work will lead to future discoveries about this important process."

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our neurology / neuroscience section for the latest news on this subject.

The research was funded by the Wellcome Trust with additional support from the EU and Medical Research Council [MRC].

Paper: The antagonistic modulation of Arp2/3 activity by N-WASP/WAVE2 and PICK1 defines dynamic changes in astrocyte morphology by Kai Murk (1), Elena M. Blanco Suarez (1), Louisa M.R. Cockbill (1), Paul Banks (2) and Jonathan G. Hanley (1) is published in advance online in the journal Cell Science. URL:

1. School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol, UK

2. School of Physiology and Pharmacology, Medical Sciences Building, University of Bristol, Bristol, UK

University of Bristol

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Rapamycin showed limited effects on aging in older mice

Main Category: Seniors / Aging
Article Date: 29 Jul 2013 - 0:00 PDT Current ratings for:
Rapamycin showed limited effects on aging in older mice

The immunosuppressive drug rapamycin has been shown to increase longevity in mice even when treatment begins at an advanced age. It is unclear if the extension of life also correlates with prolonged health and vigor.

In the current issue of the Journal of Clinical Investigation, Dan Ehninger and colleagues at the German Center for Neurodegenrative Diseases evaluated age-associated characteristics in mice treated with rapamycin. They found that rapamycin improved memory and spatial learning, reduced thyroid follicle size, and reduced body fat in older mice. However, many of these same attributes were also improved in young mice treated with the drug, indicating an age-independent drug effect.

The prevalence of cancer, a common cause of mouse mortality, was also decreased in older treated mice. The authors did find that rapamycin treatment had no effect on several age related symptoms, including cardiovascular and liver function, loss of muscle mass, strength retention, or balance.

These data suggest that rapamycin treatment may increase lifespan through reduction of cancer rates, and the drug may be useful for relief of some age related conditions.

In the accompanying commentary, Arlan Richards of the University of Texas Health Science Center at San Antonio suggests that clinical trials to study the effect of rapamycin on age related neurodegenerative diseases of the elderly such as Alzheimer's disease should be considered.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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