Five genes identified that play major role in Takayasu arteritis

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Additional authors: Travis Hughes, Kenan Aksu, Gokhan Keser, Patrick Coit, Sibel Z. Aydin,Fatma Alibaz-Oner, Sevil Kamali, Murat Inanc, Simon Carette, Gary S. Hoffman, Servet Akar, Fatos Onen, Nurullah Akkoc, Nader A. Khalidi, Curry Koening, Omer Karadag, Sedat Kiraz, Carol A. Langford, Carol A. McAlear, Zeynep Ozbalkan, Askin Ates,Yasar Karaaslan, Kathleen Maksimowicz-McKinnon, Paul A. Monach, Hu¨seyin T. Ozer, Emire Seyahi, Izzet Fresko, Ayse Cefle, Philip Seo, Kenneth J. Warrington, Mehmet A. Ozturk, Steven R. Ytterberg, Veli Cobankara, A. Mesut Onat, Joel M. Guthridge, Judith A. James, Ercan Tunc, Nursxen Duzgun, Muge Bicakcigil, Sibel P. Yentu¨r, Peter A. Merkel, Haner Direskeneli.

Disclosures: None

Funding: This work was made possible by funding from the University of Michigan, the Vasculitis Foundation, and the National Institutes of Health.

"Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis," American Journal of Human Genetics, August, 2013, doi:10.1016/j.ajhg.2013.05.026

Güher Saruhan-Direskeneli1, Travis Hughes2, Kenan Aksu3, Gokhan Keser3, Patrick Coit2, Sibel Z. Aydin4, 5, Fatma Alibaz-Oner4, Sevil Kamali6, Murat Inanc6, Simon Carette7, Gary S. Hoffman8, Servet Akar9, Fatos Onen9, Nurullah Akkoc9, Nader A. Khalidi10, Curry Koening11, Omer Karadag12, Sedat Kiraz12, Carol A. Langford8, Carol A. McAlear13, Zeynep Ozbalkan14, Askin Ates14, 15, Yasar Karaaslan14, 16, Kathleen Maksimowicz-McKinnon17, 18, Paul A. Monach19, Hüseyin T. Ozer20, Emire Seyahi21, Izzet Fresko21, Ayse Cefle22, Philip Seo23, Kenneth J. Warrington24, Mehmet A. Ozturk25, Steven R. Ytterberg24, Veli Cobankara26, A. Mesut Onat27, Joel M. Guthridge28, Judith A. James28, Ercan Tunc29, Nursen Duzgun15, Muge Bicakcigil30, Sibel P. Yentür1, Peter A. Merkel13, Haner Direskeneli4 and Amr H. Sawalha2*

Department of Physiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey Division of Rheumatology, University of Michigan, Ann Arbor, MI 48109, USA Department of Rheumatology, Faculty of Medicine, Ege University, Izmir 35100, Turkey Department of Rheumatology, Faculty of Medicine, Marmara University, Istanbul, 34890, Turkey Unit of Rheumatology, Goztepe Training and Research Hospital, Medeniyet University, Istanbul 34730, Turkey Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey Division of Rheumatology, Mount Sinai Hospital, Toronto, ON M5L 3L9, Canada Department of Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH 44195, USA Department of Rheumatology, Faculty of Medicine, Dokuz Eylül University, Izmir 35340, Turkey Division of Rheumatology, St. Joseph’s Healthcare, McMaster University, Hamilton, ON L8N 1Y2, Canada Division of Rheumatology, University of Utah, Salt Lake City, UT 84132, USA Department of Rheumatology, Faculty of Medicine, Hacettepe University, Ankara 06100, Turkey Division of Rheumatology, University of Pennsylvania, Philadelphia, PA 19104, USA Department of Rheumatology, Ankara Numune Training and Research Hospital, Ankara 06100, Turkey Department of Rheumatology, Faculty of Medicine, Ankara University, Ankara 06100, Turkey Department of Rheumatology, Faculty of Medicine, Hitit University, Çorum 19200, Turkey Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA 15261, USA Division of Rheumatology, Henry Ford Health System, Detroit, MI 48202, USA Section of Rheumatology, Boston University School of Medicine, Boston, MA 02118, USA Department of Rheumatology, Faculty of Medicine, Cukurova University, Adana 01330, Turkey Department of Rheumatology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul 34098, Turkey Department of Rheumatology, Faculty of Medicine, Kocaeli University, Kocaeli 41380, Turkey Division of Rheumatology, Johns Hopkins University, Baltimore, MD 21224, USA Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA Department of Rheumatology, Faculty of Medicine, Gazi University, Ankara 06500, Turkey Department of Rheumatology, Faculty of Medicine, Pamukkale University, Denizli 20160, Turkey Department of Rheumatology, Faculty of Medicine, Gaziantep University, Gaziantep 27310, Turkey Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA Department of Rheumatology, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey Department of Rheumatology, Faculty of Medicine, Yeditepe University, Istanbul 34752, Turkey

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University of Michigan Health System

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